Rabu, 17 Agustus 2016

Berikut Testimonial ;
Rancupsikoanalisa versi Zolmia

Pharmacological action
Zolmia is a sleeping drug from the group of imidazopyridine, specific agonist of omega1-receptors in CNS. It shortens the time to sleep, reduces the number of nighttime awakenings, increased sleep duration and improves its quality. This medication extends phase II of sleep, phases III and IV of deep sleep, does not affect the duration of REM sleep. Zolpidem characterized also by a central muscle relaxant and anticonvulsant effects.





 
ZOLMIA ZOLPIDEM - RANCUPSIKOANALISA


Zolpidem drug interactions
When Zolmia used with opioid analgesics, antitussives, barbiturates, antidepressants, sedatives, antihistamines, benzodiazepines, clonidine, neuroleptics, ethanol may develop symptoms of CNS depression and respiratory center.
When Zolmia used with rifampicin, the concentration of zolpidem in the blood plasma, which is accompanied by a decrease in its hypnotic effect. Interaction is due to induction of isoenzyme CYP3A4.
 

Simultaneous administration with inducers of CYP3A4 isoenzyme (including with carbamazepine, phenytoin) may be possible reducing the concentration of zolpidem in the blood plasma.
Simultaneous administration with clozapine increases the risk of collapse, stop breathing and circulation.


Zolmia in case of emergency / overdose
Symptoms: disturbance of consciousness (from lethargy to mild coma). There was recorded one case of cardiovascular and respiratory disorders; observed a full recovery after receiving doses of Zolmia up to 400 mg.
reatment: immediate induction of vomiting or gastric lavage (depending on state), the appointment of activated carbon. Should abandon the use of any sedative drugs (even when expressed excitation). Hemodialysis is ineffective. Specific antidote is flumazenil (benzodiazepine receptor antagonist).



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